Ultrasound imaging to monitor photothermal therapy – Feasibility study

Ultrasound and Photoacoustic Imaging to Guide and Monitor Photothermal Therapy

Longitudinal, multimodal functional imaging of microvascular response to photothermal therapy.

Although studies have shown that photothermal therapy can coagulate selectively abnormal vasculature, the ability of this method to achieve consistent, complete removal of the vasculature is questionable. We present the use of multimodal, wide-field functional imaging to study, in greater detail, the biological response to selective laser injury. Specifically, a single-platform instrument capab...

Multifunctional GQDs-Coated Fe/Bi Nanohybrids for CT/MR Dual Imaging and in vitro Photothermal Therapy

Introduction: The multipurpose nanocomposites have gained growing biomedical attention as promising nanotheranostics to improve The effectiveness of cancer treatment, which concurrently combine advantages of the therapeutic and diagnostic techniques into one nanosystem. The “all-in on” probes not only help to ablate cancerous tumors, but also allow to optimize and monitoring of...

Protein-based photothermal theranostics for imaging-guided cancer therapy.

The development of imageable photothermal theranostics has attracted considerable attention for imaging guided photothermal therapy (PTT) with high tumor ablation accuracy. In this study, we strategically constructed a near-infrared (NIR) cyanine dye by introducing a rigid cyclohexenyl ring to the heptamethine chain to obtain a heptamethine dye CySCOOH with high fluorescence intensity and good ...

Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy

Xiaolian Sun,* Xinglu Huang, Xuefeng Yan, Yu Wang, Jinxia Guo, Orit Jacobson, Dingbin Liu, Lawrence P. Szajek, Wenlei Zhu, ) Gang Niu, Dale O. Kiesewetter, Shouheng Sun, ) and Xiaoyuan Chen* Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States, Center ...